Ricerca della pubblicazione

I nostri team di ricerca e sviluppo sono distribuiti in tutto il mondo, generando sinergie grazie alle nostre competenze specializzate e discipline correlate. Partecipiamo a uno scambio internazionale con istituzioni specializzate indipendenti, opinion leader e moltiplicatori chiave, al fine di garantire la cooperazione e la gestione delle conoscenze ai massimi livelli. Come parte di questo impegno, conduciamo ricerche approfondite che vengono continuamente presentate ai congressi sotto forma di poster o conferenze dai nostri partner di cooperazione, nonché ai simposi e workshop, e pubblicati su riviste scientifiche rinomate. Le pubblicazioni specialistiche basate sulle evidenze, per lo più valutate da revisori indipendenti, sono disponibili in questo database:

  1. Poster

    AMELI ORATI ON DE LA PRI SE EN CHARGE DE PATI ENTS PORTEURS D’ULCERE VEI NEUX DE JAMBE PAR APPLI CATI ON D’UN ARBRE DECI SI ONNEL CLI NI QUE

    Poster presented at CPC 2006 15.01.2006 Paris, France
  2. Journal article

    Ulkusverkleinerung und Schmerzreduktion in der Behandlung von ulzerierenden Lymphödemen und Phlebolymphödemen mit Kurzzugbinden

    LymphForsch 2006 10(1) 3942
    Downloads Citation (RIS)
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  3. Journal article

    Multicentre, randomised controlled trial of four-layer bandaging versus short-stretch bandaging in the treatment of venous leg ulcers

    VASA. Zeitschrift fur Gefasskrankheiten 2001 30(2) 108113

    BACKGROUND

    Aim of the study was to compare the healing rates of venous ulcers obtained with four-layer bandages (4LB) versus short stretch bandages (SSB).

     

    DESIGN

    Multicentre, randomised controlled trial performed in 5 centres of the Netherlands and in 2 centres in Austria ("PADS-study" = Profore Austrian Dutch Study).

     

    PATIENTS AND METHODS

    112 patients (53 treated with 4LB and 59 treated with SSB) completed at least one post-treatment follow-up, 90 completed the study. Bandaging and ulcer assessment was performed at weekly intervals. Randomisation was carried out for each centre and was stratified according to the size (more or less than 10 cm2) of the ulcerated area. Local therapy consisted of plain absorbing, non-adherent dressings. Time to complete healing was recorded up to a maximum of 16 weeks. The two treatment-groups were comparable regarding their baseline-characteristics.

     

    RESULTS

    In total 33/53 (62%) of ulcer-patients were healed in the 4LB group, compared with 43/59 (73%) in the SSB group (difference 11%, 95% CI -28% to 7%). 77% of the ulcers with an initial area less than 5 cm2 healed as compared with 33% of the larger ulcers. The different healing rates in the centres could be explained by the different sizes of the treated ulcers. Based on Kaplan-Meier estimates the median healing time was 57 days for the 4LB (95% CI 47-85 days) and 63 days for the SSB (95% CI 43-70 days).

     

    CONCLUSION

    The ulcer healing rate and the median healing time did not differ among the two types of bandages. The main discriminant criterion for healing was the initial ulcer size. In centres who are experienced users of short-stretch bandages, no statistically significant different healing rates of venous ulcers could be found after 4LB or SSB.

    PMID 11417280
    Downloads Citation (RIS)

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