TY  - JOUR
T1  - Intraabdominal continuous negative pressure therapy for secondary peritonitis
T4  - an observational trial in a maximum care center
LA  - English
AU  - Müller, Verena
AU  - Piper, S. K.
AU  - Pratschke, J.
AU  - Raue, W.
AB  - Background: Acute secondary peritonitis is afflicted with a high morbidity and mortality. Intensive care therapy, antibiotics and surgical procedures are mandatory. Continuous negative pressure therapy (cNPT) seems to be beneficial but it is unclear which patients will benefit most from this procedures.Methods: We performed a prospective observational trial including all patients that needed to undergo an exploratory laparotomy for the suspicion of acute secondary peritonitis and were treated with cNPT in one year.Results: Thirty nine patients fitted the criteria. Median hospitalization length was 40 days. The vacuum therapy treatment was applied for a median of 4 days. The subgroup analysis between patients, who received the cNPT-dressing for one time (Group A) and patients, in whom the cNPT was continued after first relaparotomy (Group B) showed no differences concerning patients' characteristics. The Mannheimer Peritonitis Index (MPI) during the first operation was significantly correlated with the number of dressing changes (Spearman's rho 0.518, p = .002).Conclusions: Fast acting in acute secondary peritonitis for elimination of the source, abdominal lavage, derivation of the exsudat and interdisciplinary treatment is the treatment of choice. The MPI could be beneficial for the decision process of using cNPT.
DO  - 10.1080/00015458.2019.1576448
IS  - 3
PY  - 2020
SN  - 0001-5458
SP  - 179
EP  - 185
PM  - 30947631
JF  - Acta chirurgica Belgica
ER  -