Clinical Newsletter
Regular updates on our latest clinical studies.
Nuestros equipos de investigación y desarrollo operan a nivel global y generan sinergias desde nuestra experiencia colectiva y a partir de disciplinas relacionadas. Del mismo modo estamos intercambiando información constantemente a nivel internacional con instituciones técnicas independientes, importantes líderes y multiplicadores de opinión para poder garantizar una gestión de la cooperación y del conocimiento al más alto nivel. Como parte de este proceso, también llevamos a cabo una investigación exhaustiva, cuyos resultados presentamos continuamente en workshops, conferencias y simposios - tanto en forma de documentación gratuita, como en ponencias ofrecidas por nuestros socios cooperadores - así como publicaciones en prensa científica de renombre. Esta base de datos contiene un largo número de estos artículos basados en evidencias científicas, cuya mayoría ha sido evaluada por asesores independientes:
INTRODUCTION
Operative and interventional treatment of Boerhaave's syndrome include closure of the esophageal defect and drainage of the septic focus. Initial reports on the use of endoscopic vacuum therapy (EVT) of Boerhaave's syndrome are now available. This article describes the experiences gained from the clinical application in two patients using this new surgical endoscopic procedure. The current literature regarding treatment of Boerhaave's syndrome is presented.
MATERIAL AND METHODS
Open-pore drainage is endoscopically placed either through the transmural defect in the extraluminal wound cavity (intracavitary EVT) or overlapping the defect into the esophageal lumen (intraluminal EVT). The application of a negative pressure results in active drainage directed to the lumen and simultaneously in defect closure. Through these therapeutic measures the perforation defect and the septic focus can be healed. Open-pore drains are manufactured from drainage tubes and open-pore foam or an open-pore film.
RESULTS
In both patients the distal esophageal perforation defects were completely healed using EVT. In 1 patient the treatment with EVT alone lasted 8 days. For the second patient EVT was combined with an open thoracotomy for decortication of pleural empyema. The treatment with EVT lasted 23 days and 1 cycle of EVT was carried out with an new open-pore film drainage (OFD). Surgical treatment to close the defect or an esophageal resection was not necessary for both patients. In the currently available studies and single case reports of ETV for Boerhaave's syndrome, 11 patients (84 %) of a total of 13 patients have been successfully treated.
CONCLUSION
First clinical experiences have demonstrated that with EVT draining of the septic focus and closure of the Boerhaave defect at the gastroesophageal junction can be achieved. The EVT is an organ-preserving endoscopic surgical treatment, which can be an alternative and complementary to traditional surgery.
Maceration is the elixation of the skin by prolonged exposure to moisture that impedes healing due to failure of the skin protection and possible microbial infections. Modern wound dressings are expected to maintain a humid wound milieu without allowing exposure of the peri-wound skin to exudate and subsequent damage of the skin by maceration. Hence, it is of interest to analyze and compare the fluid management of PU-foam dressings under standardized conditions as close as possible to a real life situation. Therefore, a vertical maceration model using 40 mmHg compression was developed.
Aviso COFEPRIS 183300202C1039
Este sitio web contiene información sobre productos y prácticas médicas, está dirigido a una amplia audiencia y podría contener datos de productos o información que no son accesibles o válidos en su país. Tenga en cuenta que nosotros no tomamos ninguna responsabilidad por acceder a información que puede que no cumpla con algún requerimiento legal, de regulación, de registro o de uso en su país de origen. Las prácticas y regulaciones médicas pueden diferir de un país a otro.