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Clinical Newsletter

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Onze teams van Onderzoek en Ontwikkeling zijn wereldwijd werkzaam, en creëren synergieën met onze deskundigheid en verwante vakdisciplines. Wij wisselen internationaal veel van gedachten met onafhankelijke, gespecialiseerde instituten, belangrijke opinieleiders en kennisverspreiders om zo samenwerkings- en kennismanagement op het hoogste niveau te kunnen garanderen. In het kader daarvan voeren wij grote studies uit die voortdurend op congressen in de vorm van posters of lezingen van onze partners, op symposia en in workshops worden gepresenteerd, en ook in befaamde wetenschappelijke tijdschriften worden gepubliceerd. De voor het grootste deel door onafhankelijke deskundigen beoordeelde, op bewijs gebaseerde vakpublicaties stellen wij u graag in deze databank ter beschikking:

  1. Journal article

    Wundverband aus Biozellulose mit Polyhexamethylenbiguanid: Anwendungsbeobachtung von Biozellulose und Polyhexamethylen-Biguanid (Suprasorb®X+PHMB) in der Behandlung von infizierten Wunden

    skriptum Kongressjournal 2008 5 (3) 19 20
  2. Journal article

    Incidence, prevalence, and pathophysiology of acne

    Johns Hopkins Advanced Studies in Medicine 2008 8 (4) 100 105
  3. Journal article

    Inelastic compression increases venous ejection fraction more than elastic bandages in patients with superficial venous reflux

    Phlebology 2008 23 (6) 287 294

    AIM

    To investigate the influence of compression bandages, manufactured using materials with different elastic properties, on the impaired venous pumping function in patients with venous insufficiency.

     

    METHODS

    Ejection volume (EV) and ejection fraction (EF) were measured using strain gauge plethysmography distal from the patella without and with elastic and inelastic compression bandages in a total of 30 patients with major venous reflux in the great saphenous vein. The interface pressure of the bandages was measured simultaneously in the medial gaiter area. Normal values of EV and EF were obtained from 15 healthy controls.

     

    RESULTS

    Patients with venous insufficiency showed a statistically significant reduction of EV and EF compared to controls. Elastic bandages with an average pressure of 42 mm Hg in the supine position achieved a moderate increase of EV and a significant improvement of EF (p < .01), while inelastic bandages applied with comparable resting pressure (41 mm Hg) raised EV and EF into a normal range (p < .001). The improvement of the ejection fraction correlates well with the pressure differences between standing and lying (Static Stiffness Index) and between muscle systole and diastole during exercise (Pearson r = 0.69 and 0.74 respectively, p < .001). Elastic bandages applied with high stretch in order to achieve standing pressures comparable to those of inelastic bandages (>60 mm Hg) led only to a minor improvement of the venous pumping function.

     

    CONCLUSIONS

    Ejected volume and ejection fraction, which are severely reduced in venous insufficiency, can be increased by compression therapy. Inelastic compression is much more effective than elastic bandages, and is able to normalize venous pumping function. With elastic bandages EV and EF always remain below the normal range even when applied with high stretch producing a resting pressure that is barely tolerable.

    PMID 19029009
  4. Journal article

    A short review of diagnosis and compression therapy of chronic venous insufficiency

    Acta dermatovenerologica Alpina, Pannonica, et Adriatica 2008 17 (1) 17 21

    INTRODUCTION

    Chronic venous insufficiency (CVI) is a venous disorder in the lower extremities associated with changes in the skin and subcutaneous tissue. Treatment with short-stretch compression bandages is highly recommended for advanced stages of CVI.

    METHODS

    The compression systems Rosidal Sys, Porelast, Coban, and Proguide were evaluated in 4 groups of mobile and active patients (n = 18) with CVI stage II or III. Sub-bandage pressures at point B1 were measured in the upright and supine positions 30 min and 12 h after the bandage was applied. Average pressures and values of the static stiffness index (SSI) were calculated for each group.

    RESULTS

    The Porelast, Rosidal Sys and Coban systems had SSI values in excess of 10 mmHg, 30 min and 12 h after application. The corresponding values for Proguide were below 10 mmHg.

    CONCLUSION

    Porelast, Rosidal Sys and Coban are very stiff systems, whereas Proguide is more similar to long-stretch compression bandages with a lower degree of stiffness.

    Products Rosidal sys , Porelast
    PMID 18454265
  5. Poster

    Total contact cast for pressure relief in diabetic foot ulcers— provisional results of a multicentre prospective clinical evaluation in Germany

    Poster presented at SGED 2007 28.11.2007 Bern, Switzerland
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  6. Poster

    Multi-disciplinary wound care – different perspectives, different priorities, one aim.

    Poster presented at Wounds UK 2007 07.11.2007 Harrogate, UK
  7. Poster

    Reducing pain in painful wounds and treating skin damage with ActiFormCool®: Three case studies

    Poster presented at Wounds UK 2007 07.11.2007 Harrogate, UK
  8. Poster

    Treatment of a patient with painful vasculitic ulcers due to systemic lupus erythematosus

    Poster presented at Wounds UK 2007 07.11.2007 Harrogate, UK
  9. Poster

    Implementation of a structured approach to leg ulcer care

    Poster presented at Wounds UK 2007 07.11.2007 Harrogate, UK
  10. Poster

    Combination of a HydroBalance wound dressing* and a Ready-to-wear compression dressing** in the treatment of venous leg ulcers – 2 case reports

    Poster presented at DGfW 2007 09.10.2007 Berlin, Germany
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