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    Our research and development teams operate at a global level and generate synergies from our collective expertise and by drawing on related disciplines. We are also constantly exchanging information at an international level with independent technical institutions, key opinion leaders and multipliers in order to be able to ensure cooperation and knowledge management of the highest order. As part of this process, we also conduct extensive research, the results of which we continually present in workshops, at conferences and symposiums - either in documentation or talks given by our cooperation partners - and also publish in renowned scientific journals. This database contains a large number of these evidence-based scientific articles, most of which have been evaluated by independent assessors:

    1. Journal article

      An updated review of the evidence for adjustable compression wrap devices in the lower limb

      Nurse Prescribing 2017 15 613

      Compression therapy is a key component in the effective management of people with lower limb problems associated with venous, lymphatic and fat disorders such as lipoedema. Individuals with lymphoedema, venous ulceration and lipoedema often require long-term compression therapy to prevent and manage problems such as chronic ulceration and skin changes, persistent swelling and shape distortion. There are challenges in achieving acceptable, safe, effective and cost-efficient compression therapy choices. Adjustable, compression-wrap devices incorporating hook-and-loop systems present new opportunities for improving treatment outcomes, supporting patient independence and selfmanagement in the use of compression therapy.

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    2. Journal article

      A review of the evidence for adjustable compression wrap devices

      Journal of wound care 2016 25(5) 242247

      UNLABELLED

      Compression therapy is a key component in the effective management of people with lower limb problems associated with venous, lymphatic and fat disorders such as lipoedema. Individuals with lymphoedema, venous ulceration and lipoedema often require long-term compression therapy to prevent and manage problems such as chronic ulceration and skin changes, persistent swelling and shape distortion. Challenges remain in achieving acceptable, safe, effective and cost-efficient compression therapy choices. Adjustable compression wrap devices using hook and loop fasteners, commonly called VELCRO brand fasteners, present new opportunities for improving treatment outcomes, supporting patient independence and self-management in the use of compression therapy. This paper reports the findings of an evidence review of adjustable compression wrap devices in people with lymphoedema, chronic oedema, venous ulceration and lipoedema.

      DECLARATION OF INTEREST

      The authors have no conflict of interest to declare.

      PMID 27169339
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    3. Journal article

      Multinational, pilot audit of a Velcro adjustable compression wrap system for venous and lymphatic conditions

      Journal of wound care 2016 25(9) 513520

      OBJECTIVE

      The aim of this small pilot audit was to record the performance of an adjustable Velcro compression wrap, ReadyWrap, and the experiences of patients and health-care professionals using the system as a self-care option for the management of venous and lymphatic leg conditions in both the treatment and maintenance phases.

      METHOD

      This audit was held within a 4-week review period. Participants included venous leg ulcer (VLU) patients with and without oedema, and patients with lymphoedema. Where open wounds were present they were managed with debridement, skin care and dressings according to clinical need. Lymphoedema patients received manual lymphatic drainage and skin care regimens as per standard practice. The Velcro system evaluated formed part of a treatment pathway with compression bandages and/or compression hosiery as clinically indicated. Patients, carers and health-care professionals applied the garments following assessment and training. Objective data recorded included change in circumferential measurements and improvement in wound status. Observation of health-care professionals, patients and carers with regard to the comfort and ease of application/removal of the device were recorded.

      RESULTS

      There were 17 patients included in the audit. Within the 4-week period a reduction in limb circumference was recorded in all cases. Improvements in open wounds were recorded in most cases. Following the 4-week audit period 94% of the application of the device was performed by either the patient (59%) or the carer (35%) thereby reducing the health-care professional contact that was required for application.

      CONCLUSION

      Early results in this small audit demonstrate that this adjustable Velcro compression wrap may provide a simple, clinically effective and patient-acceptable solution for self-care with compression. Use of this type of device could have the potential to reduce overall health-care burden by reducing necessary skilled treatment visits and/or cost while still achieving good clinical outcomes. Further studies are required to confirm this pilot study and provide additional data.

      PMID 27608512
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    4. Journal article

      The difficulty and the solution of compression therapy in a healed venous leg ulcer

      British journal of community nursing 2016 21 Suppl 9 348

      Continuing preventative treatment once a venous ulcer is healed is fraught with dangers, with the most common problem being the inability of the wearer or their carer to apply compression therapy. A new novel compression modality has been introduced to solve the dilemma of applying compression once an injury has healed. This compression is also time-saving for practitioners who wish to heal leg ulcers. This will have an impact on the time restrictions of practice and district nurses-who have a 10-15 minute slot to dress and bandage their patients' venous ulcers.

      PMID 27594312
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    5. Poster

      Evaluation of a Tubular Compression System as an Alternative for Compression Bandages for Fragile Venous Leg Ulcer Patients

      Poster presented at Wounds UK 2015 09.11.2015 Harrogate, UK
      Products Vliwasorb
      Further versions
    6. Journal article

      Venous disease and chronic oedema: Treatment and patient concordance

      British journal of nursing (Mark Allen Publishing) 2014 23(9) 46646870

      Compression therapy is the mainstay in the management of chronic venous disease, venous leg ulceration (VLU) and chronic oedema. The management of VLU alone is thought to cost a staggering £400 million per year and accounts for 13% of all district nursing visits. The predicted increase in elderly, obese and chronically ill patients will pose a further strain on already stretched resources. The impact of chronic venous and lymphovenous disease is also costly in terms of physical and psychological terms for patients. Adopting a preventive approach would reduce the financial, workload and symptomatic aspects of this condition.

      PMID 24820810
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    7. Poster

      Management of lower limb lymphovenous oedema in a patient with paraspinal arteriovenous malformation (AVM)

      Poster presented at Wounds UK 2013 11.11.2013 Harrogate, UK

      Arteriovenous Malformation (AVM) is an abnormal connection that can affect each part

      of the vasculature (capillaries, arteries, veins or a combination of these) which usually

      are congenital. This vascular anomaly is widely known because of its occurrence in

      the central nervous system. Typically, patients with this condition seek help from a

      number of physicians only to experience disappointing outcomes, complications, and

      (Yakes, Rossi & Odink, recurrence or deterioration of their presenting symptoms

      1996). Vascular malformations constitute some of the most difficult diagnostic and

      therapeutic enigmas that can be encountered in medicine. These challenges are

      compounded by the extreme rarity of these vascular lesions and the vascular

      (Yakes, 1999 intervention required in treatment

    8. Poster

      LIVING WITH A VENOUS ARTERIAL LYMPHATIC ULCER FOR FOURTY-SEVEN YEARS – A CASE STUDY

      Poster presented at EWMA 2013 15.05.2013 Copenhagen, Denmark
    9. Journal article

      New techniques for wound debridement

      International wound journal 2013 10(3) 247251

      Debridement is a crucial component of wound management. Traditionally, several types of wound debridement techniques have been used in clinical practice such as autolytic, enzymatic, biodebridement, mechanical, conservative sharp and surgical. Various factors determine the method of choice for debridement for a particular wound such as suitability to the patient, the type of wound, its anatomical location and the extent of debridement required. Recently developed products are beginning to challenge traditional techniques that are currently used in wound bed preparation. The purpose of this review was to critically evaluate the current evidence behind the use of these newer techniques in clinical practice. There is some evidence to suggest that low frequency ultrasound therapy may improve healing rates in patients with venous ulcers and diabetic foot ulcers. Hydrosurgery debridement is quick and precise, but the current evidence is limited and further studies are underway. Debridement using a monofilament polyester fibre pad and plasma-mediated bipolar radiofrequency ablation are both very new techniques. The initial evidence is limited, and further studies are warranted to confirm their role in management of chronic wounds.

      Products Debrisoft Pad
      PMID 23418808
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    10. Journal article

      Experimental study on efficacy of compression systems with a high static stiffness index for treatment of venous ulcer patients

      Veins and Lymphatics 2013 2(1) 8

      The experimental study measured interface pressure and static stiffness index of four different compression systems in fifty-two healthy volunteers. For the study interface pressure (3 cm ø probe was placed at the anatomical B1 point) was recorded on application of the compression systems every 15 min for 4 h, in supine, standing, while sitting and during walking. For this purpose a portable Kikuhime (Harada Corp., Osaka, Japan) device was used. Further static stiffness index (SSI) was calculated. The evaluated systems were: short stretch bandage system (SSB) Rosidal sys (Lohmann & Rauscher, Rengsdorf, Germany), multi-layer bandaging (LSB) Profore (Smith & Nephew, Hull, UK), varistretch bandage (VSB) Proguide (Smith & Nephew) and tubular compression (CS) Rosidal mobil (Lohmann & Rauscher). The mean interface pressure of SSB, LSB and VSB was significantly higher (P<0.05) in each position measured over 4 h, compared to CS. In supine VSB showed high-pressure levels, up to 60 mmHg, which remained high. The other systems had more tolerable levels of about 30 mmHg. Interface pressure exerted on limbs is an indicator of their clinical effect. The experimental study results showed different patterns of interface pressure and SSI, which may enable clinicians to predict the frequency of bandage application, supporting an adequate and safe choice of bandage system.

      Products Rosidal sys
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