Clinical Newsletter
Regular updates on our latest clinical studies.
Our research and development teams operate at a global level and generate synergies from our collective expertise and by drawing on related disciplines. We are also constantly exchanging information at an international level with independent technical institutions, key opinion leaders and multipliers in order to be able to ensure cooperation and knowledge management of the highest order. As part of this process, we also conduct extensive research, the results of which we continually present in workshops, at conferences and symposiums - either in documentation or talks given by our cooperation partners - and also publish in renowned scientific journals. This database contains a large number of these evidence-based scientific articles, most of which have been evaluated by independent assessors:
Introduction:
Infection of the wound site can lead to the formation of a chronic wound. Pathogenecity and density of the colonizing microbes influence infection severity. However, when host defense mechanisms are impaired the risk of infection increases. Nosocomial infections have multiplied dramatically in the last years. Important pathogens of nosocomial infections are Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa, Escherichia coli and Candida albicans. The spread of these pathogens can only be inhibited through consistent hygiene sanctions and preventive disinfectant actions. Polyacrylate-superabsorber containing wound dressings are able to take up large quantities of exudates while keeping the wound environment moist; an additional inhibition of bacterial and fungal growth would be a beneficial attribute. We have tested three different polyacrylate-superabsorber containing wound dressings according to the JIS L 1902for antibacterial and antifungal activity.
Material & Methods:
Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa, Escherichia coli and Candida albicans were chosen to monitor the antimicrobial effect. According to the JIS L 1902 norm samples of 400 mg of the polyacrylate-superabsorber containing wound dressings (Vliwasorb, Lohmann & Rauscher; Zetuvit plus, Hartmann; Sorbion sachet, Sorbion AG) were used for testing. The samples were incubated with the experimental pathogens(Staphylococcus aureus: 6,3·105cfu/mL, Klebsiella pneumoniae: 5,9·105cfu/mL,Pseudomonas aeruginosa: 9,1·105cfu/mL, Escherichia coli: 6,2·105cfu/mL und Candida albicans: 1,5·104cfu/mL) up to 24 h at 37C under aerobic conditions.
Results:
The polyacrylate-superabsorber containing wound dressings showed a strong inhibitory effect on Klebsiella pneumoniae, Pseudomonas aeruginos and Escherichia coli. They were also able to inhibit the growth of Staphylococcus aureus and Candida albicans significantly.
Conclusions:
The polyacrylate-superabsorber containing wound dressing exhibit a distinct antibacterial and antifungal activity. Its use should help to treat wound infections by entrapment of the microorganisms in the forming gel on exudates’ uptake and inhibition of their growth.
This article reports an observational evaluation of 19 patients with highly exuding wounds. Flivasorb was used as a super absorbent dressing that could remove the harmful exudate fluid and promote a healthy wound bed. The outcomes demonstrated that Flivasorb is successfully absorbs large amounts of fluid, reduces the number of dressing changes required and therefore, reduces the cost of the patient's care.
C commonly performed under general anesthetic with difficulties in managing postoperative analgesia requirements resulting in slow LC mobilization and recovery. In-patient stays of 2 weeks are commonplace and care is often disjointed with limited interaction between the LC different groups of health care providers. Changing demographics and an ever-increasing demand for joint replacement dictate that the LLC processes be streamlined to maximize efficiency. Rapid Recovery is an evidence-based means of providing the best possible patient care, LL while at the same time optimizing the use of resources. It promotes patient centered care with a focus on patient education and LL prehabilitation. The preoperative, intraoperative, and postoperative stages of Rapid Recovery are described. The significant reduction in the L length of in-patient stay, the considerable cost savings, and the low complication rates are discussed as well as the favorable patient L satisfaction scores. Rapid Recovery should now be thought of as the gold standard for the treatment of all patients undergoing hip and knee replacement. C There is traditionally an unnecessary ‘‘medicalization’’ of the orthopedic patient undergoing total knee arthroplasty. Such procedures are
Aims: The objective of this prospective randomised comparative study was to assess the effects of two different cellulose-based dressings and their influence on venous leg ulcer cleansing and debridement over a four-week observation period. Methods: After ethics committee approval was obtained, both in and outpatients at the trial centres were recruited to the study after giving written informed consent. Forty patients (n=20/20) were included on an intention to treat basis. Results: Forty patients completed the study (n=20/n=20) and were included in the analysis. The ulcers in the study group (SG) showed a 43.53% reduction in wound area, whereas the ulcers in the control group (CG) had a 17.94% reduction. The reduction of yellow tissue was significantly larger in the SG (t=0.020 at day 7 and t=0.45 at day 14; 75.2% at baseline, 16.5% at 28 days) than in the CG (80.2% at baseline, 34.5% at 28 days). Pain reduction was faster and better in the SG (visual analogue scale [VAS] 1.30) at 28 days than in the CG (VAS 3.20). Conclusions: Both cellulose-based dressings were found to be successful in wound cleansing. Pain reduction was faster and better in the SG, contributing to an improved quality of life. Conflict of interest: This study was supported by Lohmann & Rauscher GmbH.
Polyhexamethylene biguanide (PHMB) has been available as a wound irrigation fluid in Europe for some time. Recently, it has been successfully introduced into wound management within a range of dressings, including non-adherent products, gauze, drains, intravenous sponges and hydrogels. In some cases, the PHMB molecule has been chemically bound to the base material, providing it with antiseptic/antimicrobial properties when in contact with wound moisture. In other products, the active component is free to be delivered into the wound and periwound tissues, serving as a carrier for a wider antimicrobial activity by donating PHMB to the wound surfa
This website contains information on products and medical practices which is targeted to a wide range of audiences and could contain product details or information otherwise not accessible or valid in your country. Please be aware that we do not take any responsibility for accessing such information which may not comply with any legal process, regulation, registration or usage in the country of your origin. Medical practices and regulations can be different from one country to another.